2 products were found matching "490463"!

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Item number: Cay40463-25

GMB 475 is a proteolysis-targeting chimera (PROTAC) containing the Bcr-Abl inhibitor GNF-5 (Cay-16254) conjugated to VHL ligand 1 (Cay-21591). It induces degradation of Bcr-Abl with a half-maximal degradation concentration (DC50) value of 340 nM. GMB 475 selectively inhibits the proliferation of K562 chronic myeloid...

Keywords:	(4R)-3-methyl-N-[2-[2-[4-[6-[[4-(trifluoromethoxy)phenyl]amino]-4-pyrimidinyl]phenoxy]ethoxy]acetyl]-L-valyl-4-hydroxy-N-[...
Application:	Bcr-Abl degradation driving PROTAC
CAS	2490599-18-1
MW:	861.9 D

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3,5-Diiodothyroacetic Acid

Item number: Cay22108-10

3,5-Diiodothyroacetic acid is an acetic acid derivative of thyroxine (Cay-14116). It inhibits copper-induced lipid peroxidation of LDL isolated from human plasma when used at a concentration of 1 µM. 3,5-Diiodothyroacetic acid (5 mg/100 g diet) increases urinary and fecal excretion of sterols, as well as prevents...

Keywords:	Diac, NSC 90463, 4-(4-hydroxyphenoxy)-3,5-diiodo-benzeneacetic acid
Application:	Calorigenic
CAS	1155-40-4
MW:	496 D

From 102.00€ *

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