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This gene encodes a complex glycoprotein secreted in plasma. The precursor is proteolytically processed into distinct functioning proteins: alpha-1-microglobulin, which belongs to the superfamily of lipocalin transport proteins and may play a role in the regulation of inflammatory processes, and bikunin, which is a...

This gene encodes a 50-kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of...

CD18 is a 90-95 kD type I transmembrane protein also known as integrin beta2 subunit, LFA-1 beta subunit, and beta2 integrin. CD18 non-covalently associates with CD11a, CD11b or CD11c. CD18 is expressed on all leukocytes. CD18 and associated alpha chains function in adhesion and signaling in hematopoietic cells....

Clusterin, also known as apolipoprotein J and sulfated glycoprotein 2, is a multifunctional secreted protein that is widely expressed in tissues. The amino acid sequence of human Clusterin is 98%, 79%, 77%, 76% and 48% identical to that of chimpanzee, canine, rat, mouse and chicken. , , Applications:, Suitable for...

Alpha-synuclein (amino acids 1-140), an acidic neuronal protein of 140 amino acids, is extremely heat-resistant and is natively unfolded with an extended structure primarily composed of random coils. Alpha-synuclein has been suggested to be implicated in the pathogenesis of Parkinson's disease and related...

Clusterin, also known as apolipoprotein J and sulfated glycoprotein 2, is a multifunctional secreted protein that is widely expressed in tissues. The amino acid sequence of human Clusterin is 98%, 79%, 77%, 76% and 48% identical to that of chimpanzee, canine, rat, mouse and chicken. Applications: Suitable for use in...

Control Peptide for 146047. Source: Synthetic peptide corresponding to 15aa from near the N-terminus of human TOR. Applications: Suitable for use in ELISA and Antibody Blocking. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be...

Control Peptide for 151472. Source: Synthetic peptide corresponding to MED15. Applications: Suitable for use in ELISA and Antibody Blocking. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only....

This gene is a member of the ecto-nucleotide pyrophosphatase/phosphodiesterase (ENPP) family. The encoded protein is a type II transmembrane glycoprotein comprising two identical disulfide-bonded subunits. This protein has broad specificity and cleaves a variety of substrates, including phosphodiester bonds of...

Catalytic subunit of the NatB complex which catalyzes acetylation of the N-terminal methionine residues of peptides beginning with Met-Asp, Met-Glu, Met-Asn and Met-Gln. Proteins with cell cycle functions are overrepresented in the pool of NatB substrates. Required for maintaining the structure and function of...

Clusterin, also known as Apolipoprotein J (ApoJ), is a ubiquitous multifunctional glycoprotein that can interact with a broad spectrum of molecules such as complement components, various receptors, and the Alzheimer's b-amyloid peptide. Clusterin expression is increased in Alzheimer's disease brain tissue and...

May play a role in the structural integrity of cartilage via its interaction with other extracellular matrix proteins such as the collagens and fibronectin. Can mediate the interaction of chondrocytes with the cartilage extracellular matrix through interaction with cell surface integrin receptors. Could play a role...