ZNRF3 Protein, Human, Recombinant (His)

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
TGM-TMPH-01275-20ug	20 µg		-		5 - 10 business days*		165.00€
TGM-TMPH-01275-100ug	100 µg		-		5 - 10 business days*		356.00€

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Description: E3 ubiquitin-protein ligase that acts as a negative regulator of the Wnt signaling... more

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Product information "ZNRF3 Protein, Human, Recombinant (His)"

Description: E3 ubiquitin-protein ligase that acts as a negative regulator of the Wnt signaling pathway by mediating the ubiquitination and subsequent degradation of Wnt receptor complex components Frizzled and LRP6. Acts on both canonical and non-canonical Wnt signaling pathway. Acts as a tumor suppressor in the intestinal stem cell zone by inhibiting the Wnt signaling pathway, thereby resticting the size of the intestinal stem cell zone. Along with RSPO2 and RNF43, constitutes a master switch that governs limb specification.

Keywords:	ZNRF3, RING-type E3 ubiquitin transferase ZNRF3, RING finger protein 203, Zinc/RING finger protein 3, E3 ubiquitin-protein ligase ZNRF3
Supplier:	TargetMol
Supplier-Nr:	TMPH-01275

Properties

Conjugate:	No
MW:	20.4 kD

Database Information

KEGG ID :	K16273 \| Matching products
UniProt ID :	Q9ULT6 \| Matching products
Gene ID :	GeneID 84133 \| Matching products

Handling & Safety

Storage:	-20°C
Shipping:	+20°C (International: +4°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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