ZNRF3 (human), recombinant protein

ZNRF3 (human), recombinant protein
Item number Size Datasheet Manual SDS Delivery time Quantity Price
ABS-PP-25468-L.20 20 µg - -

10 - 15 business days*

115.00€
ABS-PP-25468-L.100 100 µg - -

10 - 15 business days*

205.00€
 
Protein function: E3 ubiquitin-protein ligase that acts as a negative regulator of the Wnt... more
Product information "ZNRF3 (human), recombinant protein"
Protein function: E3 ubiquitin-protein ligase that acts as a negative regulator of the Wnt signaling pathway by mediating the ubiquitination and subsequent degradation of Wnt receptor complex components Frizzled and LRP6. Acts on both canonical and non-canonical Wnt signaling pathway. Acts as a tumor suppressor in the intestinal stem cell zone by inhibiting the Wnt signaling pathway, thereby resticting the size of the intestinal stem cell zone (PubMed:22575959). Along with RSPO2 and RNF43, constitutes a master switch that governs limb specification. [The UniProt Consortium]
Keywords: ZNRF3, KIAA1133, EC=2.3.2.27, RING finger protein 203, Zinc/RING finger protein 3, E3 ubiquitin-protein ligase ZNRF3, RING-type E3 ubiquitin transferase ZNRF3
Supplier: Absea
Supplier-Nr: PP-25468-L

Properties

Conjugate: No
Host: E.coli
Species reactivity: human
MW: 18 kD
Purity: >85%
Format: Lyophilized

Handling & Safety

Storage: -20°C (protect from light & moisture)
Shipping: +20°C (International: +20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow. more
You will get a certificate here
or to request a certificate of analysis.
Read, write and discuss reviews... more
Customer review for "ZNRF3 (human), recombinant protein"
Write a review
or to review a product.
Viewed