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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
AG-40T-0103-C050 | 50 µg | - |
3 - 9 business days* |
495.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Prefered cleavage sequence is PxxF. Full-length Zmp1 (Mycobacterium tuberculosis) is fused at the... more
Product information "Zmp1 (M. tuberculosis) (rec.) (His)"
Prefered cleavage sequence is PxxF. Full-length Zmp1 (Mycobacterium tuberculosis) is fused at the N-terminus to a His-tag. Liquid. In 10mM TRIS-HCl, pH 8.0. M13 endopeptidases are single-pass, transmembrane zinc-metallopeptidases responsible in human for the regulation of the biological activity of many hormones and peptides and are involved in many important processes such as blood pressure regulation (Neprilysin or NEP1), cardiovascular development (Endothelin Converting Enzyme-1 or ECE-12), prevention of haemolytic reaction (KELL) and phosphate homeostasis (PHEX). Zmp1 is a soluble enzyme member of the M13 endopeptidases family that plays a key role in Mycobacterium tuberculosis pathogenicity with a still unknown mechanism. Recently, it was shown to suppress inflammasome activation by inhibiting caspase-1 activation, thus preventing processing of pro-IL-1beta into IL-1beta and the consequent phagosome maturation.
Keywords: | zmp1, MT0208, Probable zinc metalloprotease Zmp1, Endopeptidase, peptidase family M13 |
Supplier: | AdipoGen Life Sciences |
Supplier-Nr: | AG-40T-0103 |
Properties
Application: | Enzyme assays |
Conjugate: | No |
Host: | E.coli |
Species reactivity: | M. tuberculosis |
MW: | 73.9 kD |
Format: | Liquid |
Database Information
KEGG ID : | K07386 | Matching products |
UniProt ID : | O53649 | Matching products |
Gene ID | GeneID 13316183 | Matching products |
Handling & Safety
Storage: | -80°C |
Shipping: | -20°C (International: -20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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