ZC3HC1 (human), recombinant protein

ZC3HC1 (human), recombinant protein
Item number Size Datasheet Manual SDS Delivery time Quantity Price
ABS-PP-10150-L.20 20 µg - -

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115.00€
ABS-PP-10150-L.100 100 µg - -

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205.00€
 
Protein function: Essential component of a SCF-type E3 ligase complex, SCF(NIPA), a complex that... more
Product information "ZC3HC1 (human), recombinant protein"
Protein function: Essential component of a SCF-type E3 ligase complex, SCF(NIPA), a complex that controls mitotic entry by mediating ubiquitination and subsequent degradation of cyclin B1 (CCNB1). Its cell-cycle-dependent phosphorylation regulates the assembly of the SCF(NIPA) complex, restricting CCNB1 ubiquitination activity to interphase. Its inactivation results in nuclear accumulation of CCNB1 in interphase and premature mitotic entry. May have an antiapoptotic role in NPM-ALK-mediated signaling events. [The UniProt Consortium]
Keywords: Zinc finger C3HC-type protein 1, Nuclear-interacting partner of ALK, hNIPA, Nuclear-interacting partner of anaplastic lymphoma kinase, Recombinant Human ZC3HC1 Protein
Supplier: Absea
Supplier-Nr: PP-10150-L

Properties

Conjugate: No
Host: E.coli
Species reactivity: human
MW: 18 kD
Format: Lyophilized

Database Information

UniProt ID : Q86WB0 | Matching products
Gene ID : GeneID 51530 | Matching products

Handling & Safety

Storage: -20°C (protect from light & moisture)
Shipping: +20°C (International: +20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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