WWP1 (human), recombinant protein

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ABS-PP-8967-L.20	20 µg		-	-	Request delivery time estimate		115.00€
ABS-PP-8967-L.100	100 µg		-	-	Request delivery time estimate		205.00€

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Protein function: E3 ubiquitin-protein ligase which accepts ubiquitin from an E2... more

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Product information "WWP1 (human), recombinant protein"

Protein function: E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Ubiquitinates ERBB4 isoforms JM-A CYT-1 and JM-B CYT-1, KLF2, KLF5 and TP63 and promotes their proteasomal degradation. Ubiquitinates RNF11 without targeting it for degradation. Ubiquitinates and promotes degradation of TGFBR1, the ubiquitination is enhanced by SMAD7. Ubiquitinates SMAD6 and SMAD7. Ubiquitinates and promotes degradation of SMAD2 in response to TGF-beta signaling, which requires interaction with TGIF. [The UniProt Consortium]

Keywords:	NEDD4-like E3 ubiquitin-protein ligase WWP1, Atrophin-1-interacting protein 5, AIP5, HECT-type E3 ubiquitin transferase WWP1, TGIF-interacting ubiquitin ligase 1, Tiul1, WW domain-containing protein 1, Recombinant Human WWP1 Protein
Supplier:	Absea
Supplier-Nr:	PP-8967-L

Properties

Conjugate:	No
Host:	E.coli
Species reactivity:	human
MW:	18 kD
Format:	Lyophilized

Database Information

KEGG ID :	K05633 \| Matching products
UniProt ID :	Q9H0M0 \| Matching products
Gene ID :	GeneID 11059 \| Matching products

Handling & Safety

Storage:	-20°C (protect from light & moisture)
Shipping:	+20°C (International: +20°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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