WNK3 (human), recombinant protein

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ABS-PP-9285-L.20	20 µg	-	-	-	Request delivery time estimate		115.00€
ABS-PP-9285-L.100	100 µg	-	-	-	Request delivery time estimate		205.00€

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Protein function: Serine/threonine kinase which plays an important role in the regulation of... more

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Product information "WNK3 (human), recombinant protein"

Protein function: Serine/threonine kinase which plays an important role in the regulation of electrolyte homeostasis, cell signaling, survival and proliferation. Acts as an activator and inhibitor of sodium-coupled chloride cotransporters and potassium-coupled chloride cotransporters respectively (PubMed:16275913, PubMed:16275911, PubMed:16357011). Phosphorylates WNK4. Regulates the phosphorylation of SLC12A1 and SLC12A2. Increases Ca(2+) influx mediated by TRPV5 and TRPV6 by enhancing their membrane expression level via a kinase-dependent pathway (PubMed:18768590). Inhibits the activity of KCNJ1 by decreasing its expression at the cell membrane in a non-catalytic manner. [The UniProt Consortium]

Keywords:	Serine/threonine-protein kinase WNK3, Protein kinase lysine-deficient 3, Protein kinase with no lysine 3, Recombinant Human WNK3 Protein
Supplier:	Absea
Supplier-Nr:	PP-9285-L

Properties

Conjugate:	No
Host:	E.coli
Species reactivity:	human
MW:	23.5 kD
Format:	Lyophilized

Database Information

KEGG ID :	K08867 \| Matching products
UniProt ID :	Q9BYP7 \| Matching products
Gene ID :	GeneID 65267 \| Matching products

Handling & Safety

Storage:	-20°C (protect from light & moisture)
Shipping:	+20°C (International: +20°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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