USP5 (human), recombinant protein

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ABS-PP-4872-L.20	20 µg		-	-	10 - 15 business days*		115.00€
ABS-PP-4872-L.100	100 µg		-	-	10 - 15 business days*		205.00€

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Protein function: Cleaves linear and branched multiubiquitin polymers with a marked preference... more

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Product information "USP5 (human), recombinant protein"

Protein function: Cleaves linear and branched multiubiquitin polymers with a marked preference for branched polymers. Involved in unanchored 'Lys- 48'-linked polyubiquitin disassembly. Binds linear and 'Lys-63'-linked polyubiquitin with a lower affinity. Knock-down of USP5 causes the accumulation of p53/TP53 and an increase in p53/TP53 transcriptional activity because the unanchored polyubiquitin that accumulates is able to compete with ubiquitinated p53/TP53 but not with MDM2 for proteasomal recognition. [The UniProt Consortium]

Keywords:	Ubiquitin carboxyl-terminal hydrolase 5, Deubiquitinating enzyme 5, Isopeptidase T, Ubiquitin thioesterase 5, Ubiquitin-specific-processing protease 5, Recombinant Human USP5 Protein
Supplier:	Absea
Supplier-Nr:	PP-4872-L

Properties

Conjugate:	No
Host:	E.coli
Species reactivity:	human
MW:	33.5 kD
Format:	Lyophilized

Database Information

KEGG ID :	K11836 \| Matching products
UniProt ID :	P45974 \| Matching products
Gene ID :	GeneID 8078 \| Matching products

Handling & Safety

Storage:	-20°C (protect from light & moisture)
Shipping:	+20°C (International: +20°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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