Ubiquitin-Conjugating Enzyme E2 R2/UBE2R2/UBC3B Protein(N-6His) (recombinant human)

Protein Construction: Recombinant Human Ubiquitin-Conjugating Enzyme E2 R2 is produced by our E.coli expression system and the target gene encoding Met1-Ser238 is expressed with a 6His tag at the N-terminus. Sequence: Met 1-Ser238. Fusion tag: N-6His Endotoxin: < 1.0 EU per µg as determined by the LAL method. Apparent Molecular Mass: 37 kDa. Protein function: Ubiquitin-Conjugating Enzyme E2 R2 (UBE2R2) is a modification enzyme that belongs to the ubiquitin-conjugating enzyme family. UBE2R2 is involved in cell growth and transformation. It accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro, UBE2R2 catalyzes monoubiquitination and 'Lys-48'-linked polyubiquitination. It may be involved in degradation of katenin. Protein function: Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes monoubiquitination and 'Lys-48'-linked polyubiquitination. May be involved in degradation of katenin. [The UniProt Consortium]