UBE2V2 protein-HIS Epitope

Recombinant human UBE2V2 (2-end) was expressed in E. coli cells using an N-Terminal his epitope. The purity was determined to be >95% by densitometry. Protein function: Has no ubiquitin ligase activity on its own. The UBE2V2/UBE2N heterodimer catalyzes the synthesis of non-canonical poly-ubiquitin chains that are linked through 'Lys-63'. This type of poly-ubiquitination does not lead to protein degradation by the proteasome. Mediates transcriptional activation of target genes. Plays a role in the control of progress through the cell cycle and differentiation. Plays a role in the error-free DNA repair pathway and contributes to the survival of cells after DNA damage. [The UniProt Consortium]