UBE2N, Recombinant, Human, aa1-152, His-tag (Ubiquitin-conjugating Enzyme E2 N, Ubiquitin-protein L

UBE2N, Recombinant, Human, aa1-152, His-tag (Ubiquitin-conjugating Enzyme E2 N, Ubiquitin-protein L
Item number Size Datasheet Manual SDS Delivery time Quantity Price
U1000-92Z.100 100 µg - -

1 - 19 business days

451.00€
 
UBE2N, also known as UBC13, is a member of the E2 ubiquitin-conjugating enzyme family. It... more
Product information "UBE2N, Recombinant, Human, aa1-152, His-tag (Ubiquitin-conjugating Enzyme E2 N, Ubiquitin-protein L"
UBE2N, also known as UBC13, is a member of the E2 ubiquitin-conjugating enzyme family. It catalyzes the ATP-dependent synthesis of non-canonical polyubiquitin chains, a process that does not lead to proteasomal degradation. It mediates the transcription of several target genes and is thought to play a role in cell cycle progression, cellular differentiation and DNA repair mechanisms that ensure cell survival after DNA damage. Source: Recombinant corresponding to aa1-152 from human UBE2N, fused to His-tag at N-terminus expressed in E. coli. AA Sequence: MGSSHHHHHH SSGLVPRGSH MAGLPRRIIK ETQRLLAEPV PGIKAEPDES NARYFHVVIA GPQDSPFEGG TFKLELFLPE EYPMAAPKVR FMTKIYHPNV DKLGRICLDI LKDKWSPALQ IRTVLLSIQA LLSAPNPDDP LANDVAEQWK TNEAQAIETA RAWTRLYAMN NI, Molecular Weight: ~19.3kD (172aa), confirmed by MALDI-TOF, Enzyme Activity: Not determined. This product is recommended for use in applications that do not require a catalytically active form of the protein. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Keywords: EC=6.3.2.19, Ubiquitin-protein ligase N, Ubiquitin carrier protein N, Ubiquitin-conjugating enzyme E2 N, Bendless-like ubiquitin-conjugating enzyme
Supplier: United States Biological
Supplier-Nr: U1000-92Z

Properties

Conjugate: No
MW: 19,3 kD
Format: Highly Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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