UBE2A (human), recombinant protein

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ABS-PP-25554.20	20 µg		-	-	10 - 15 business days*		90.00€
ABS-PP-25554.100	100 µg		-	-	10 - 15 business days*		180.00€

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Protein function: Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to... more

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Product information "UBE2A (human), recombinant protein"

Protein function: Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In association with the E3 enzyme BRE1 (RNF20 and/or RNF40), it plays a role in transcription regulation by catalyzing the monoubiquitination of histone H2B at 'Lys- 120' to form H2BK120ub1. H2BK120ub1 gives a specific tag for epigenetic transcriptional activation, elongation by RNA polymerase II, telomeric silencing, and is also a prerequisite for H3K4me and H3K79me formation. In vitro catalyzes 'Lys-11', as well as 'Lys-48'-linked polyubiquitination. Required for postreplication repair of UV-damaged DNA. [The UniProt Consortium]

Keywords:	HR6A, UBE2A, RAD6A, hHR6A, RAD6 homolog A, Ubiquitin-protein ligase A, Ubiquitin carrier protein A, E2 ubiquitin-conjugating enzyme A, Ubiquitin-conjugating enzyme E2 A
Supplier:	Absea
Supplier-Nr:	PP-25554

Properties

Conjugate:	No
Host:	E.coli
Species reactivity:	human
MW:	18.5 kD
Purity:	>85%
Format:	Solution

Database Information

KEGG ID :	K10573 \| Matching products
UniProt ID :	P49459 \| Matching products
Gene ID :	GeneID 7319 \| Matching products

Handling & Safety

Storage:	-20°C (avoid repeat freezing and thawing cycles)
Shipping:	-20°C (International: -20°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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