TREM2 Protein, Cynomolgus, Recombinant (His)

TREM2 Protein, Cynomolgus, Recombinant (His)

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
TGM-TMPK-00507-100ug	100 µg		-		7 - 10 business days*		350.00€
TGM-TMPK-00507-500ug	500 µg		-		7 - 10 business days*		1,412.00€

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Description: TREM-2 (Triggering Receptor Expressed on Myeloid cells-2) is a 35 kDa type I... more

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Product information "TREM2 Protein, Cynomolgus, Recombinant (His)"

Description: TREM-2 (Triggering Receptor Expressed on Myeloid cells-2) is a 35 kDa type I transmembrane member of the TREM family and Ig superfamily. Mature human TREM-2 consists of a 156 amino acid (aa) extracellular domain (ECD) with one V-type Ig-like domain, a 21 aa transmembrane (TM) domain, and a 35 aa cytoplasmic tail. TREM-2 forms a receptor signaling complex with TYROBP which mediates signaling and cell activation following ligand binding (PubMed:10799849). Acts as a receptor for amyloid-beta protein 42, a cleavage product of the amyloid-beta precursor protein APP, and mediates its uptake and degradation by microglia.

Keywords:	TREM-2, Trem2c, Trem2b, TREM2, Trem2a, PLOSL2
Supplier:	TargetMol
Supplier-Nr:	TMPK-00507

Properties

Conjugate:	No
MW:	18.5 kD

Database Information

UniProt ID :

A0A2K5UY39 | Matching products

Handling & Safety

Storage:	-20°C
Shipping:	+4°C (International: +4°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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