TREM2[Biotin], His & Avi, Human

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
GSC-Z04636-100	100 µg		-		Request delivery time estimate		887.00€
GSC-Z04636-500	500 µg		-		Request delivery time estimate		2,943.00€

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TREM-2 (Triggering Receptor Expressed on Myeloid cells-2) is a 35 kDa type I transmembrane member... more

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Product information "TREM2[Biotin], His & Avi, Human"

TREM-2 (Triggering Receptor Expressed on Myeloid cells-2) is a 35 kDa type I transmembrane member of the TREM family and Ig superfamily. Mature human TREM-2 consists of a 156 amino acid (aa) extracellular domain (ECD) with one V-type Ig-like domain, a 21 aa transmembrane (TM) domain, and a 35 aa cytoplasmic tail. TREM-2 forms a receptor signaling complex with TYROBP which mediates signaling and cell activation following ligand binding (PubMed:10799849). Acts as a receptor for amyloid-beta protein 42, a cleavage product of the amyloid-beta precursor protein APP, and mediates its uptake and degradation by microglia.

Keywords:	TREM2, Triggering receptor expressed on monocytes 2, Triggering receptor expressed on myeloid cells 2
Supplier:	GenScript
Supplier-Nr:	Z04636

Properties

Conjugate:	Biotin
Species reactivity:	human
MW:	20.3 kD
Purity:	>95% (Bis-Tris PAGE)

Database Information

KEGG ID :	K14378 \| Matching products
UniProt ID :	Q9NZC2 \| Matching products
Gene ID :	GeneID 54209 \| Matching products

Handling & Safety

Storage:	-20°C
Shipping:	+4°C (International: °C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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