Trefoil Factor 1, active (TFF1), Recombinant, Human

Stabilizer of the mucous gel overlying the gastrointestinal mucosa that provides a physical barrier against various noxious agents. May inhibit the growth of calcium oxalate crystals in urine. {ECO:0000269, PubMed:16308573}. Biological Activity: Fully biologically active when compared to standard. The ED50 as determined by a chemotaxis bioassay using human MCF-7 cells is less than 10ug/ml, corresponding to a specific activity of ? 100 IU/mg. Sequence: EAQTETCTVA PRERQNCGFP GVTPSQCANK GCCFDDTVRG VPWCFYPNTI DVPPEEECEF, Molecular Weight: 6.7kD, PubMed ID: 6324130, 3838275, 3822834, 2311759, 2185238, 10950923, 10830953, 15489334, 3146413, 15924415, 16308573, 3261981, 15340161, 3041593, 16718800, 17143957, 17242463, 8521850, 9096235, 10982763, 16697734, Gene Name: TFF1,BCEI,PS2, Swiss Prot: P04155, Storage and Stability: Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.