Transferrin, Mouse, Highly Purified

Transferrin is a single polypeptide chain glycoprotein. It is a member of the iron binding family of proteins. It has a MW of 79.5kD. It is synthesized in the liver and consists of two domains each having a high affinity reversible binding site for Fe3+. The iron is transported in blood and interstitial fluids to sites of use and disposal. Iron/transferrin is essential in hemoglobin synthesis and for certain types of cell division. Serum concentration range is 1800-2700mg/L. Serum concentration rises in iron deficiency and pregnancy. Serum concentration falls in iron overload, infection and inflammatory conditions. Applications: Suitable for use as a control or standard in ELISA, Western Blot and conjugation. Other applications have not been tested. Recommended Dilutions: Optimal dilutions to be determined by researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Dilute only prior to immediate use.