Transferrin, Bovine, Iron Saturated (HOLO), USA Origin

Transferrin is a single polypeptide chain glycoprotein and is a member of the iron binding family of proteins. It has a molecular weight of 79.5kD and a serum concentration range of 1800-2700mg/L. It is synthesized in the liver and consists of two domains each having a high affinity reversible binding site for Fe3+. The iron is transported in blood and interstitial fluids to sites of use and disposal. Iron/transferrin is essential in hemoglobin synthesis and for certain types of cell division. Serum concentration rises in iron deficiency and pregnancy and falls in iron overload, infection and inflammatory conditions. Transferrin is a single polypeptide chain glycoprotein and is a member of the iron binding family of proteins. It has a molecular weight of 79.5kD and a serum concentration range of 1800-2700mg/L. It is synthesized in the liver and consists of two domains each having a high affinity reversible binding site for Fe3+. The iron is transported in blood and interstitial fluids to sites of use and disposal. Iron/transferrin is essential in hemoglobin synthesis and for certain types of cell division. Serum concentration rises in iron deficiency and pregnancy and falls in iron overload, infection and inflammatory conditions. , Isolated from fresh bovine plasma from certified USA herds and tested for adventitious viruses, bovine transferrin is an essential cellular transport protein via receptor-mediated endocytosis. Suitable for use in serum-free media and RPMI.. Certificate of Origin: All raw material used in the manufacturing of Transferrin is of US origin and was manufactured in USDA-registered plants. The animals used received both ante- and post-mortem inspections under certified veterinary care and were inspected to be free of apparent infectious and contagious diseases infections and injurious parasites known to be transferable to hoofed animals, such as blue-tongue fever. In addition, all material was heated during processing to a temperature exceeding (65°C) for a period of 10 hours and subjected to a pH of 5.0 or lower for at least 3 hours. Foot and mouth disease, rinderpest, contagious bovine pleuropneumonia, hog cholera, swine vesticular disease and African swine fever are not known to exist in the United States. Age of bovine raw material is less than 3 years.