TRAIL R2/DR5/TNFRSF10B Protein, Human, Recombinant (hFc)

Item number	Size	Manual	Delivery time	Price
TGM-TMPK-00277-100ug	100 µg	-	7 - 10 business days*	345.00€
TGM-TMPK-00277-500ug	500 µg	-	7 - 10 business days*	1,400.00€
TGM-TMPK-00277-1mg	1 mg		7 - 10 business days*	2,332.00€

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Description: DR5, also called TRAIL R2, TRICK 2, TNFRSF10B, and MK is a type 1 TNF R superfamily,... more

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Product information "TRAIL R2/DR5/TNFRSF10B Protein, Human, Recombinant (hFc)"

Description: DR5, also called TRAIL R2, TRICK 2, TNFRSF10B, and MK is a type 1 TNF R superfamily, membrane protein which is a receptor for TRAIL (APO2 ligand). DR5 is a receptor for the cytotoxic ligand TNFSF10/TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis.

Keywords:	TRAIL receptor 2, Fas-like protein, DR5, TRAIL R2, TNFRSF10B, TRICK2, KILLER, DR5TRICK2B, CD262, TRICK2A, KILLER/DR5, ZTNFR9, TRICKB, TRAILR2
Supplier:	TargetMol
Supplier-Nr:	TMPK-00277

Properties

Conjugate:	No
MW:	41.1 kD

Database Information

KEGG ID :	K04722 \| Matching products
UniProt ID :	O14763 \| Matching products
Gene ID :	GeneID 8795 \| Matching products

Handling & Safety

Storage:	-20°C
Shipping:	+4°C (International: +4°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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