TRAIL-R1 (human):Fc (human, rec.)

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
AG-40B-0070-C050	50 µg		-		3 - 9 business days*		204.00€
AG-40B-0070-3050	150 µg (3 x 50 µg)		-		3 - 9 business days*		407.00€

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(3 x 50µg). The extracellular domain of human TRAIL-R1 (amino acids 24-239) is fused to the Fc... more

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Product information "TRAIL-R1 (human):Fc (human, rec.)"

(3 x 50µg). The extracellular domain of human TRAIL-R1 (amino acids 24-239) is fused to the Fc portion of human IgG1. Blocks human or mouse TRAIL activity in a concentration of 1-10µg/ml. Lyophilized. Contains PBS. TRAIL-R1 (DR4, CD261) is a receptor for the cytotoxic ligand TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappaB.

Keywords:	DR4, TNFRSF 10A, APO2, CD261, TRAIL receptor 1, TNF-related apoptosis-inducing ligand receptor 1
Supplier:	AdipoGen Life Sciences
Supplier-Nr:	AG-40B-0070

Properties

Application:	Bioassays
Conjugate:	No
Host:	Human cells
Species reactivity:	human, mouse
MW:	52 kD
Format:	Lyophilized

Database Information

KEGG ID :	K04722 \| Matching products
UniProt ID :	O00220 \| Matching products

Handling & Safety

Storage:	-20°C
Shipping:	+4°C (International: +4°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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