TRAF3IP2 PrEST Antigen

TRAF3IP2 PrEST Antigen
Item number Size Datasheet Manual SDS Delivery time Quantity Price
ATA-APrEST77277.100 100 µl - -

3 - 8 business days*

264.00€
 
Protein function: E3 ubiquitin ligase that catalyzes 'Lys-63'-linked polyubiquitination of target... more
Product information "TRAF3IP2 PrEST Antigen"
Protein function: E3 ubiquitin ligase that catalyzes 'Lys-63'-linked polyubiquitination of target protein, enhancing protein-protein interaction and cell signaling (PubMed:19825828). Transfers ubiquitin from E2 ubiquitin-conjugating enzyme UBE2V1-UBE2N to substrate protein (PubMed:19825828). Essential adapter molecule in IL17A-mediated signaling (PubMed:19825828, PubMed:24120361). Upon IL17A stimulation, interacts with IL17RA and IL17RC receptor chains through SEFIR domains and catalyzes 'Lys-63'-linked polyubiquitination of TRAF6, leading to TRAF6-mediated activation of NF-kappa-B and MAPkinase pathways (PubMed:19825828). [The UniProt Consortium] Buffer: PBS and 1M Urea, pH 7.4.
Keywords: ACT1, C6orf2, TRAF3IP2, Adapter protein CIKS, TRAF3-interacting protein 2, E3 ubiquitin ligase TRAF3IP2, Connection to IKK and SAPK/JNK, E3 ubiquitin-protein ligase CIKS, Nuclear factor NF-kappa-B activator 1
Supplier: Atlas Antibodies
Supplier-Nr: APrEST77277

Properties

Application: Control antigen
Conjugate: No
Host: E.coli
Species reactivity: human

Handling & Safety

Storage: -20°C (avoid repeat freezing and thawing cycles)
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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