TNFRSF10A (human), recombinant protein

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ABS-PQ-330.20	20 µg	-	-	-	Request delivery time estimate		270.00€
ABS-PQ-330.100	100 µg	-	-	-	Request delivery time estimate		540.00€

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Protein function: Receptor for the cytotoxic ligand TNFSF10/TRAIL (PubMed:26457518). The adapter... more

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Product information "TNFRSF10A (human), recombinant protein"

Protein function: Receptor for the cytotoxic ligand TNFSF10/TRAIL (PubMed:26457518). The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis (PubMed:19090789). Promotes the activation of NF- kappa-B (PubMed:9430227). [The UniProt Consortium]

Keywords:	Tumor necrosis factor receptor superfamily member 10A, Death receptor 4, TNF-related apoptosis-inducing ligand receptor 1, TRAIL receptor 1, TRAIL-R1, CD antigen CD261, Recombinant Human TNFRSF10A Protein
Supplier:	Absea
Supplier-Nr:	PQ-330

Properties

Conjugate:	No
Host:	human cells
Species reactivity:	human
MW:	37.5 kD
Format:	Solution

Database Information

KEGG ID :	K04722 \| Matching products
UniProt ID :	O00220 \| Matching products
Gene ID :	GeneID 8797 \| Matching products

Handling & Safety

Storage:	-20°C (avoid repeat freezing and thawing cycles)
Shipping:	-20°C (International: -20°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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