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TNFR2/CD120b/TNFRSF1B [Biotin], His, Human

GenScript
TNFR2/CD120b/TNFRSF1B [Biotin], His, Human
Item number Size Datasheet Manual SDS Delivery time Quantity Price
GSC-Z04627-100 100 µg -

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887.00€
GSC-Z04627-500 500 µg -

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2,943.00€
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Description Product Citations Certificate of Analysis Reviews 0
Description
Tumor Necrosis Factor Receptor II (TNF RII), also known as TNFRSF1B, p75/p80, and CD120b, is a... more
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Product information "TNFR2/CD120b/TNFRSF1B [Biotin], His, Human"
Tumor Necrosis Factor Receptor II (TNF RII), also known as TNFRSF1B, p75/p80, and CD120b, is a type I transmembrane protein that belongs to the TNF receptor superfamily. It has a molecular weight of approximately 75 kDa.Receptor with high affinity for TNFSF2/TNF-alpha and approximately 5-fold lower affinity for homotrimeric TNFSF1/lymphotoxin-alpha. The TRAF1/TRAF2 complex recruits the apoptotic suppressors BIRC2 and BIRC3 to TNFRSF1B/TNFR2. This receptor mediates most of the metabolic effects of TNF-alpha. Isoform 2 blocks TNF-alpha-induced apoptosis, which suggests that it regulates TNF-alpha function by antagonizing its biological activity.
Keywords: p75, TNFRSF1B, p80 TNF-alpha receptor, Tumor necrosis factor receptor 2, Tumor necrosis factor receptor type II, Tumor necrosis factor receptor superfamily member 1B
Supplier: GenScript
Supplier-Nr: Z04627

Properties

Conjugate: Biotin
Species reactivity: human
MW: 26.2 kD
Purity: >95% (Bis-Tris PAGE)

Database Information

KEGG ID : K05141 | Matching products
UniProt ID : P20333 | Matching products
Gene ID : GeneID 7133 | Matching products

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: °C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
Product Citations
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