TLK1 (human), recombinant protein

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ABS-PP-10180-L.20	20 µg	-	-	-	Request delivery time estimate		115.00€
ABS-PP-10180-L.100	100 µg	-	-	-	Request delivery time estimate		205.00€

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Protein function: Rapidly and transiently inhibited by phosphorylation following the generation... more

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Product information "TLK1 (human), recombinant protein"

Protein function: Rapidly and transiently inhibited by phosphorylation following the generation of DNA double-stranded breaks during S-phase. This is cell cycle checkpoint and ATM-pathway dependent and appears to regulate processes involved in chromatin assembly. Isoform 3 phosphorylates and enhances the stability of the t-SNARE SNAP23, augmenting its assembly with syntaxin. Isoform 3 protects the cells from the ionizing radiation by facilitating the repair of DSBs. In vitro, phosphorylates histone H3 at 'Ser-10'. [The UniProt Consortium]

Keywords:	Serine/threonine-protein kinase tousled-like 1, PKU-beta, Tousled-like kinase 1, Recombinant Human TLK1 Protein
Supplier:	Absea
Supplier-Nr:	PP-10180-L

Properties

Conjugate:	No
Host:	E.coli
Species reactivity:	human
MW:	12.5 kD
Format:	Lyophilized

Database Information

KEGG ID :	K08864 \| Matching products
UniProt ID :	Q9UKI8 \| Matching products
Gene ID :	GeneID 9874 \| Matching products

Handling & Safety

Storage:	-20°C (protect from light & moisture)
Shipping:	+20°C (International: +20°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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