TIPRL (human), recombinant protein

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ABS-PP-1968-L.20	20 µg	-	-	-	Request delivery time estimate		115.00€
ABS-PP-1968-L.100	100 µg	-	-	-	Request delivery time estimate		205.00€

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Protein function: May be a allosteric regulator of serine/threonine-protein phosphatase 2A... more

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Product information "TIPRL (human), recombinant protein"

Protein function: May be a allosteric regulator of serine/threonine-protein phosphatase 2A (PP2A). Isoform 1 inhibits catalytic activity of the PP2A(D) core complex in vitro. The PP2A(C):TIPRL complex does not show phosphatase activity. Acts as negative regulator of serine/threonine- protein phosphatase 4 probably by inhibiting the formation of the active PPP4C:PPP4R2 complex, the function is proposed to implicate it in DNA damage response by promoting H2AX phosphorylated on Ser-140 (gamma-H2AX). May play a role in the regulation of ATM/ATR signaling pathway controlling DNA replication and repair. [The UniProt Consortium]

Keywords:	TIP41-like protein, Putative MAPK-activating protein PM10, Type 2A-interacting protein, TIP, Recombinant Human TIPRL Protein
Supplier:	Absea
Supplier-Nr:	PP-1968-L

Properties

Conjugate:	No
Host:	E.coli
Species reactivity:	human
MW:	16 kD
Format:	Lyophilized

Database Information

KEGG ID :	K17607 \| Matching products
UniProt ID :	O75663 \| Matching products
Gene ID :	GeneID 261726 \| Matching products

Handling & Safety

Storage:	-20°C (protect from light & moisture)
Shipping:	+20°C (International: +20°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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