TIM-3/HAVCR2, His, Mouse

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Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
GSC-Z06374-100	100 µg		-		7-10 business days*		578.00€
GSC-Z06374-500	500 µg		-		7-10 business days*		1,935.00€

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Hepatitis A virus cellular receptor 2 (HAVCR2), also known as T-cell immunoglobulin and... more

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Product information "TIM-3/HAVCR2, His, Mouse"

Hepatitis A virus cellular receptor 2 (HAVCR2), also known as T-cell immunoglobulin and mucin-domain containing-3 (TIM-3), is a protein that in humans is encoded by the HAVCR2 gene.TIM3 is an immune checkpoint and together with other inhibitory receptors including programmed cell death protein 1 (PD-1) and lymphocyte activation gene 3 protein (LAG3) mediate the CD8 T-cell exhaustion. TIM3 has also been shown as a CD4 Th1-specific cell surface protein that regulates macrophage activation and enhances the severity of experimental autoimmune encephalomyelitis in mice.

Keywords:	Havcr2, T-cell membrane protein 3, T-cell immunoglobulin mucin receptor 3, Hepatitis A virus cellular receptor 2 homolog, T-cell immunoglobulin and mucin domain-containing protein 3
Supplier:	GenScript
Supplier-Nr:	Z06374

Properties

Conjugate:	No
Species reactivity:	mouse
MW:	19.9, kD
Purity:	>95% (Bis-Tris PAGE)

Database Information

KEGG ID :	K20414 \| Matching products
UniProt ID :	Q8VIM0 \| Matching products
Gene ID :	GeneID 171285 \| Matching products

Handling & Safety

Storage:	-20°C
Shipping:	+4°C (International: °C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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