THOC3 PrEST Antigen

THOC3 PrEST Antigen
Item number Size Datasheet Manual SDS Delivery time Quantity Price
ATA-APrEST82635.100 100 µl - -

7 - 10 business days*

264.00€
 
Protein function: Required for efficient export of polyadenylated RNA and spliced mRNA. Acts as... more
Product information "THOC3 PrEST Antigen"
Protein function: Required for efficient export of polyadenylated RNA and spliced mRNA. Acts as component of the THO subcomplex of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and which specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap- dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NFX1 pathway. The TREX complex is essential for the export of Kaposi's sarcoma-associated herpesvirus (KSHV) intronless mRNAs and infectious virus production. [The UniProt Consortium] Buffer: PBS and 1M Urea, pH 7.4.
Keywords: Tho3, THOC3, hTREX45, TEX1 homolog, THO complex subunit 3
Supplier: Atlas Antibodies
Supplier-Nr: APrEST82635

Properties

Application: Control antigen
Conjugate: No
Host: E.coli
Species reactivity: human

Handling & Safety

Storage: -20°C (avoid repeat freezing and thawing cycles)
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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