THG1L (human), recombinant protein

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ABS-PP-13920.20	20 µg		-	-	10 - 15 business days*		90.00€
ABS-PP-13920.100	100 µg		-	-	10 - 15 business days*		180.00€

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Protein function: Adds a GMP to the 5'-end of tRNA(His) after transcription and RNase P cleavage.... more

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Product information "THG1L (human), recombinant protein"

Protein function: Adds a GMP to the 5'-end of tRNA(His) after transcription and RNase P cleavage. This step is essential for proper recognition of the tRNA and for the fidelity of protein synthesis (Probable). Also functions as a guanyl-nucleotide exchange factor/GEF for the MFN1 and MFN2 mitofusins thereby regulating mitochondrial fusion (PubMed:25008184, PubMed:27307223). By regulating both mitochondrial dynamics and bioenergetic function, it contributes to cell survival following oxidative stress (PubMed:25008184, PubMed:27307223). [The UniProt Consortium]

Keywords:	IHG-1, ICF45, THG1L, Induced in high glucose-1, tRNA-histidine guanylyltransferase, Interphase cytoplasmic foci protein 45, Probable tRNA(His) guanylyltransferase
Supplier:	Absea
Supplier-Nr:	PP-13920

Properties

Conjugate:	No
Host:	E.coli
Species reactivity:	human
MW:	17.5 kD
Purity:	>85%
Format:	Solution

Database Information

KEGG ID :	K10761 \| Matching products
UniProt ID :	Q9NWX6 \| Matching products
Gene ID :	GeneID 54974 \| Matching products

Handling & Safety

Storage:	-20°C (avoid repeat freezing and thawing cycles)
Shipping:	-20°C (International: -20°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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