TFB2M PrEST Antigen

TFB2M PrEST Antigen
Item number Size Datasheet Manual SDS Delivery time Quantity Price
ATA-APrEST92122.100 100 µl - -

3 - 8 business days*

264.00€
 
Protein function: S-adenosyl-L-methionine-dependent rRNA methyltransferase which may methylate... more
Product information "TFB2M PrEST Antigen"
Protein function: S-adenosyl-L-methionine-dependent rRNA methyltransferase which may methylate two specific adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 12S mitochondrial rRNA (Probable). Component of the mitochondrial transcription initiation complex, composed at least of TFB2M, TFAM and POLRMT that is required for basal transcription of mitochondrial DNA (PubMed:29149603, PubMed:12068295, PubMed:20410300, PubMed:15526033). In this complex, TFAM recruits POLRMT to a specific promoter whereas TFB2M induces structural changes in POLRMT to enable promoter opening and trapping of the DNA non- template strand (PubMed:29149603, PubMed:15526033). Stimulates transcription independently of the methyltransferase activity (PubMed:12897151). [The UniProt Consortium] Buffer: PBS and 1M Urea, pH 7.4.
Keywords: mtTFB2, hTFB2M, NS5ATP5, h-mtTFB, h-mtTFB2, HCV NS5A-transactivated protein 5, Mitochondrial 12S rRNA dimethylase 2, Mitochondrial transcription factor B2, Dimethyladenosine transferase 2, mitochondrial
Supplier: Atlas Antibodies
Supplier-Nr: APrEST92122

Properties

Application: Control antigen
Conjugate: No
Host: E.coli
Species reactivity: human

Handling & Safety

Storage: -20°C (avoid repeat freezing and thawing cycles)
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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