Testican-3/SPOCK3 Protein(C-6His) (recombinant mouse)

Protein Construction: Recombinant Mouse Testican-3 is produced by our Mammalian expression system and the target gene encoding Ala23-Ile436 is expressed with a 6His tag at the C-terminus. Sequence: Ala23-Ile436. Fusion tag: C-6His Endotoxin: < 1.0 EU per µg as determined by the LAL method. Apparent Molecular Mass: 58-60 kDa. Protein function: Testican3, also called SPOCK3, is a secreted protein and make up a family of extracellular heparan/chondroitin sulfate proteoglycans. It contains 1 Kazal-like domain and 1 thyroglobulin type-1 domain. Testican3 contain inhibitory regions in several domains targeted to different classes of protease, and in some cases may act as protease inhibitors. In addition to their presence in testis, testicans are enriched in brain and have been shown to regulate neuronal attachment and outgrowth. It may participate in diverse steps of neurogenesis and Inhibits the processing of pro-matrix metalloproteinase 2 (MMP-2) by MT1-MMP and MT3-MMP. It also may interfere with tumor invasion. Protein function: May participate in diverse steps of neurogenesis. Inhibits the processing of pro-matrix metalloproteinase 2 (MMP-2) by MT1-MMP and MT3-MMP. May interfere with tumor invasion. [The UniProt Consortium]