TCF3 (human), recombinant protein

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ABS-PP-4768-L.20	20 µg		-	-	Request delivery time estimate		115.00€
ABS-PP-4768-L.100	100 µg		-	-	Request delivery time estimate		205.00€

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Protein function: Transcriptional regulator involved in the initiation of neuronal... more

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Product information "TCF3 (human), recombinant protein"

Protein function: Transcriptional regulator involved in the initiation of neuronal differentiation and mesenchymal to epithelial transition. Heterodimers between TCF3 and tissue-specific basic helix-loop-helix (bHLH) proteins play major roles in determining tissue-specific cell fate during embryogenesis, like muscle or early B-cell differentiation. Together with TCF15, required for the mesenchymal to epithelial transition. Dimers bind DNA on E-box motifs: 5'-CANNTG-3'. Binds to the kappa-E2 site in the kappa immunoglobulin gene enhancer (PubMed:2493990). Binds to IEB1 and IEB2, which are short DNA sequences in the insulin gene transcription control region. [The UniProt Consortium]

Keywords:	Transcription factor E2-alpha, Class B basic helix-loop-helix protein 21, bHLHb21, Immunoglobulin enhancer-binding factor E12/E47, Immunoglobulin transcription factor 1, Kappa-E2-binding factor, Transcription factor 3, TCF-3, Transcription factor ITF-1, R
Supplier:	Absea
Supplier-Nr:	PP-4768-L

Properties

Conjugate:	No
Host:	E.coli
Species reactivity:	human
MW:	18.5 kD
Format:	Lyophilized

Database Information

KEGG ID :	K09063 \| Matching products
UniProt ID :	P15923 \| Matching products
Gene ID :	GeneID 6929 \| Matching products

Handling & Safety

Storage:	-20°C (protect from light & moisture)
Shipping:	+20°C (International: +20°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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