T-cell immunoglobulin and mucin domain-containing protein 4 (TIMD4), partial, human, recombinant

Organism: Homo sapiens (Human). Source: Mammalian cell. Expression Region: 25-314aa. Protein Length: Partial. Tag Info: C-terminal hFc-tagged. Target Protein Sequence: ETVVTEVLGH RVTLPCLYSS WSHNSNSMCW GKDQCPYSGC KEALIRTDGM RVTSRKSAKY RLQGTIPRGD VSLTILNPSE SDSGVYCCRI EVPGWFNDVK INVRLNLQRA STTTHRTATT TTRRTTTTSP TTTRQMTTTP AALPTTVVTT PDLTTGTPLQ MTTIAVFTTA NTCLSLTPST LPEEATGLLT PEPSKEGPIL TAESETVLPS DSWSSVESTS ADTVLLTSKE SKVWDLPSTS HVSMWKTSDS VSSPQPGASD TAVPEQNKTT KTGQMDGIPM SMKNEMPISQ. Purity: Greater than 85% as determined by SDS-PAGE. Endotoxin: Not test. Biological Activity: n/a. Form: Liquid or Lyophilized powder. Buffer: If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0. Reconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20 °C/-80 °C. Our default final concentration of glycerol is 50%. Customers could use it as reference. Storage: The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 °C/-80 °C. The shelf life of lyophilized form is 12 months at -20 °C/-80 °C. Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4 °C for up to one week. Relevance: Phosphatidylserine receptor that enhances the engulfment of apoptotic cells. Involved in regulating T-cell proliferation and lymphotoxin signaling. Ligand for HAVCR1/TIMD1. Reference: "Genetic association studies between the T cell immunoglobulin mucin (TIM) gene locus and childhood atopic dermatitis." Page N.S., Jones G., Stewart G.J. Int. Arch. Allergy Immunol. 141:331-336(2006). Function: nan