Surfeit 1, Recombinant Human, His tag, 80-273aa (SURF1)

SURF1, also known as surfeit 1, is a member of the SURF1 family, which includes the related yeast protein SHY1 and rickettsial protein RP733. This protein is localized to the inner mitochondrial membrane and thought to be involved in the biogenesis of the cytochrome c oxidase complex. Defects in SURF1 is a cause of Leigh syndrome, a severe neurological disorder that is commonly associated with systemic cytochrome c oxidase deficiency. Recombinant SURF1 protein was expressed in E. coli and purified by using conventional chromatography techniques. Source: Recombinant corresponding to human SURF1, expressed in E. coli. AA sequence: MGSSHHHHHH SSGLVPRGSH MQVQRRKWKL NLIAELESRV LAEPVPLPAD PMELKNLEYR PVKVRGCFDH SKELYMMPRT MVDPVREARE GGLISSSTQS GAYVVTPFHC TDLGVTILVN RGFVPRKKVN PETRQKGQIE GEVDLIGMVR LTETRQPFVP ENNPERNHWH YRDLEAMARI TGAEPIFIDA NFQSTVPGGP IGGQTRVTLR NEHLQ, Enzyme Activity: Not determined. This product is recommended for use in applications that do not require a catalytically active form of the protein. Storage and Stability: Aliquot to avoid repeated freezing and thawing and freeze at -70°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquots are stable for at least 6 months.