STK36 PrEST Antigen

STK36 PrEST Antigen
Item number Size Datasheet Manual SDS Delivery time Quantity Price
ATA-APrEST77834.100 100 µl - -

7 - 10 business days*

247.00€
 
Protein function: Serine/threonine protein kinase which plays an important role in the sonic... more
Product information "STK36 PrEST Antigen"
Protein function: Serine/threonine protein kinase which plays an important role in the sonic hedgehog (Shh) pathway by regulating the activity of GLI transcription factors (PubMed:10806483). Controls the activity of the transcriptional regulators GLI1, GLI2 and GLI3 by opposing the effect of SUFU and promoting their nuclear localization (PubMed:10806483). GLI2 requires an additional function of STK36 to become transcriptionally active, but the enzyme does not need to possess an active kinase catalytic site for this to occur (PubMed:10806483). Required for postnatal development, possibly by regulating the homeostasis of cerebral spinal fluid or ciliary function. Essential for construction of the central pair apparatus of motile cilia. [The UniProt Consortium] Buffer: PBS and 1M Urea, pH 7.4.
Keywords: EC=2.7.11.1, Fused homolog, Serine/threonine-protein kinase 36
Supplier: Atlas Antibodies
Supplier-Nr: APrEST77834

Properties

Application: Control antigen
Conjugate: No
Host: E.coli
Species reactivity: human

Handling & Safety

Storage: -20°C (avoid repeat freezing and thawing cycles)
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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