STAT3 protein-GST fusion

STAT3 protein-GST fusion
Item number Size Datasheet Manual SDS Delivery time Quantity Price
009-001-T53S 20 µg - -

6 - 10 business days*

533.00€
 
Recombinant full-length human STAT3 was expressed by baculovirus in Sf9 insect cells using an... more
Product information "STAT3 protein-GST fusion"
Recombinant full-length human STAT3 was expressed by baculovirus in Sf9 insect cells using an N-Terminal Glutathione-S-Transferase fusion protein. The purity was determined to be >90% by densitometry. Protein function: Signal transducer and transcription activator that mediates cellular responses to interleukins, KITLG/SCF and other growth factors. May mediate cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4. Binds to the interleukin-6 (IL-6)- responsive elements identified in the promoters of various acute- phase protein genes. Activated by IL31 through IL31RA. Cytoplasmic STAT3 represses macroautophagy by inhibiting EIF2AK2/PKR activity. Plays an important role in host defense in methicillin-resistant S.aureus lung infection by regulating the expression of the antimicrobial lectin REG3G. [The UniProt Consortium]
Keywords: APRF, STAT3, Acute-phase response factor, Signal transducer and activator of transcription 3
Supplier: Rockland Immunochemicals
Supplier-Nr: 009-001-T53S

Properties

Application: WB
Conjugate: No
Host: Human

Handling & Safety

Storage: -80°C
Shipping: -20°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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