ST8SIA1 (human), recombinant protein

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ABS-PQ-646.20	20 µg	-	-	-	Request delivery time estimate		270.00€
ABS-PQ-646.100	100 µg	-	-	-	Request delivery time estimate		540.00€

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Protein function: Catalyzes the addition of sialic acid in alpha 2,8-linkage to the sialic acid... more

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Product information "ST8SIA1 (human), recombinant protein"

Protein function: Catalyzes the addition of sialic acid in alpha 2,8-linkage to the sialic acid moiety of the ganglioside GM3 to form ganglioside GD3, gangliosides are a subfamily of complex glycosphinglolipds that contain one or more residues of sialic acid (PubMed:7937974, PubMed:8058740, PubMed:8195250, PubMed:8631981, PubMed:8706663, PubMed:18348864, PubMed:22885356). Can catalyze the addition of a second alpha-2,8- sialic acid to GD3 to form GT3 (PubMed:8631981). Can use GM1b, GD1a and GT1b as acceptor substrates to synthesize GD1c, GT1a and GQ1b respectively (PubMed:8706663). Can synthesize unusual tetra- and pentasialylated lactosylceramide derivatives identified as GQ3 (II3Neu5Ac4-Gg2Cer) and GP3 (II3Neu5Ac5-Gg2Cer) in breast cancer cells (PubMed:22885356). [The UniProt Consortium]

Keywords:	Alpha-N-acetylneuraminide alpha-2, 8-sialyltransferase, Alpha-2, 8-sialyltransferase 8A, Ganglioside GD3 synthase, Ganglioside GT3 synthase, Sialyltransferase 8A, SIAT8-A, Sialyltransferase St8Sia I, ST8SiaI, Recombinant Human ST8SIA1 Protein
Supplier:	Absea
Supplier-Nr:	PQ-646

Properties

Conjugate:	No
Host:	human cells
Species reactivity:	human
MW:	56 kD
Format:	Solution

Database Information

KEGG ID :	K03371 \| Matching products
UniProt ID :	Q92185 \| Matching products
Gene ID :	GeneID 6489 \| Matching products

Handling & Safety

Storage:	-20°C (avoid repeat freezing and thawing cycles)
Shipping:	-20°C (International: -20°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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