SPP1/OPN, His, Human

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
GSC-Z05855-100	100 µg		-		7 - 10 business days*		497.00€
GSC-Z05855-500	500 µg		-		7 - 10 business days*		1,680.00€

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Ovarian cancer is one of the most lethal malignant tumors in women. Secreted phosphoprotein 1... more

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Product information "SPP1/OPN, His, Human"

Ovarian cancer is one of the most lethal malignant tumors in women. Secreted phosphoprotein 1 (SPP1) plays an important role in some cancer types. The expression of SPP1 was higher in epithelial ovarian cancer tissues than in normal ovarian tissues. Silencing SPP1 decreased the cell proliferation, migration, and invasion. Ectopic expression of SPP1 increased the cell proliferation, migration, and invasion. Silencing SPP1 prevented ovarian cancer growth in mice. Silencing SPP1 inhibited Integrin beta1/FAK/AKT pathway.

Keywords:	SPP1, Uropontin, Osteopontin, Nephropontin, Bone sialoprotein 1, Urinary stone protein, Secreted phosphoprotein 1
Supplier:	GenScript
Supplier-Nr:	Z05855

Properties

Conjugate:	No
Species reactivity:	human
MW:	34.8 kD
Purity:	>95% (Bis-Tris PAGE)

Database Information

KEGG ID :	K06250 \| Matching products
UniProt ID :	P10451 \| Matching products
Gene ID :	GeneID 6696 \| Matching products

Handling & Safety

Storage:	-20°C
Shipping:	+4°C (International: °C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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