SPATA13 (human), recombinant protein

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ABS-PP-7332.20	20 µg	-	-	-	Request delivery time estimate		90.00€
ABS-PP-7332.100	100 µg	-	-	-	Request delivery time estimate		180.00€

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Protein function: Acts as guanine nucleotide exchange factor (GEF) for RHOA, RAC1 and CDC42... more

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Product information "SPATA13 (human), recombinant protein"

Protein function: Acts as guanine nucleotide exchange factor (GEF) for RHOA, RAC1 and CDC42 GTPases. Regulates cell migration and adhesion assembly and disassembly through a RAC1, PI3K, RHOA and AKT1-dependent mechanism. Increases both RAC1 and CDC42 activity, but decreases the amount of active RHOA. Required for MMP9 up-regulation via the JNK signaling pathway in colorectal tumor cells. Involved in tumor angiogenesis and may play a role in intestinal adenoma formation and tumor progression. [The UniProt Consortium]

Keywords:	Spermatogenesis-associated protein 13, APC-stimulated guanine nucleotide exchange factor 2, Asef2, Recombinant Human SPATA13 Protein
Supplier:	Absea
Supplier-Nr:	PP-7332

Properties

Conjugate:	No
Host:	E.coli
Species reactivity:	human
MW:	16 kD
Format:	Solution

Database Information

KEGG ID :	K05769 \| Matching products
UniProt ID :	Q96N96 \| Matching products
Gene ID :	GeneID 221178 \| Matching products

Handling & Safety

Storage:	-20°C (avoid repeat freezing and thawing cycles)
Shipping:	-20°C (International: -20°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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