SOX30 (human), recombinant protein

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ABS-PP-6522.20	20 µg	-	-	-	Request delivery time estimate		90.00€
ABS-PP-6522.100	100 µg	-	-	-	Request delivery time estimate		180.00€

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Protein function: Acts as both a transcriptional activator and repressor (PubMed:10359848,... more

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Product information "SOX30 (human), recombinant protein"

Protein function: Acts as both a transcriptional activator and repressor (PubMed:10359848, PubMed:29739711). Binds to the DNA sequence 5'-ACAAT- 3' and shows a preference for guanine residues surrounding this core motif (PubMed:10359848). Binds to its own promoter and activates its own transcription. Required to activate the expression of postmeiotic genes involved in spermiogenesis. Binds to the promoter region of CTNNB1 and represses its transcription which leads to inhibition of Wnt signaling (PubMed:29739711). Also inhibits Wnt signaling by binding to the CTNNB1 protein, preventing interaction of CTNNB1 with TCF7L2/TCF4 (PubMed:29739711). [The UniProt Consortium]

Keywords:	Transcription factor SOX-30, Recombinant Human SOX30 Protein
Supplier:	Absea
Supplier-Nr:	PP-6522

Properties

Conjugate:	No
Host:	E.coli
Species reactivity:	human
MW:	35.5 kD
Format:	Solution

Database Information

KEGG ID :	K09271 \| Matching products
UniProt ID :	O94993 \| Matching products
Gene ID :	GeneID 11063 \| Matching products

Handling & Safety

Storage:	-20°C (avoid repeat freezing and thawing cycles)
Shipping:	-20°C (International: -20°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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