SNRPB2, Recombinant, Human, aa1-225, His-tag (U2 snRNP B)

SNRPB2, also known as U2 small nuclear ribonucleoprotein B, belongs to the RRM U1 A/B family. This protein associates with stem loop IV of U2 small nuclear ribonucleoprotein (U2 snRNP) in the presence of snRNP-A. It may play a role in pre-mRNA splicing. Autoantibodies from patients with systemic lupus erythematosus frequently recognize epitopes on the encoded protein. Two transcript variants encoding the same protein have been found for this gene. Source: Recombinant corresponding to aa1-225 from human SNRPB2, fused to His-tag at N-terminus expressed in E.coli. AA Sequence: MGSSHHHHHH SSGLVPRGSH MDIRPNHTIY INNMNDKIKK EELKRSLYAL FSQFGHVVDI VALKTMKMRG QAFVIFKELG SSTNALRQLQ GFPFYGKPMR IQYAKTDSDI ISKMRGTFAD KEKKKEKKKA KTVEQTATTT NKKPGQGTPN SANTQGNSTP NPQVPDYPPN YILFLNNLPE , ETNEMMLSML FNQFPGFKEV RLVPGRHDIA FVEFENDGQA GAARDALQGF KITPSHAMKI TYAKK, Molecular Weight: ~27.6kD (245aa), confirmed by MALDI-TOF, Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.