SMURF1 (human), recombinant protein

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ABS-PP-5459-L.20	20 µg		-	-	Request delivery time estimate		115.00€
ABS-PP-5459-L.100	100 µg		-	-	Request delivery time estimate		205.00€

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Protein function: E3 ubiquitin-protein ligase that acts as a negative regulator of BMP signaling... more

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Product information "SMURF1 (human), recombinant protein"

Protein function: E3 ubiquitin-protein ligase that acts as a negative regulator of BMP signaling pathway. Mediates ubiquitination and degradation of SMAD1 and SMAD5, 2 receptor-regulated SMADs specific for the BMP pathway. Promotes ubiquitination and subsequent proteasomal degradation of TRAF family members and RHOA. Promotes ubiquitination and subsequent proteasomal degradation of MAVS (PubMed:23087404). Plays a role in dendrite formation by melanocytes (PubMed:23999003). [The UniProt Consortium]

Keywords:	E3 ubiquitin-protein ligase SMURF1, hSMURF1, HECT-type E3 ubiquitin transferase SMURF1, SMAD ubiquitination regulatory factor 1, SMAD-specific E3 ubiquitin-protein ligase 1, Recombinant Human SMURF1 Protein
Supplier:	Absea
Supplier-Nr:	PP-5459-L

Properties

Conjugate:	No
Host:	E.coli
Species reactivity:	human
MW:	24 kD
Format:	Lyophilized

Database Information

KEGG ID :	K04678 \| Matching products
UniProt ID :	Q9HCE7 \| Matching products
Gene ID :	GeneID 57154 \| Matching products

Handling & Safety

Storage:	-20°C (protect from light & moisture)
Shipping:	+20°C (International: +20°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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