SMG8 (human), recombinant protein

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ABS-PP-7136-L.20	20 µg	-	-	-	Request delivery time estimate		115.00€
ABS-PP-7136-L.100	100 µg	-	-	-	Request delivery time estimate		205.00€

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Protein function: Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop... more

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Product information "SMG8 (human), recombinant protein"

Protein function: Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons. Is recruited by release factors to stalled ribosomes together with SMG1 and SMG9 (forming the SMG1C protein kinase complex) and, in the SMG1C complex, is required to mediate the recruitment of SMG1 to the ribosome:SURF complex and to suppress SMG1 kinase activity until the ribosome:SURF complex locates the exon junction complex (EJC). Acts as a regulator of kinase activity. [The UniProt Consortium]

Keywords:	Nonsense-mediated mRNA decay factor SMG8, Amplified in breast cancer gene 2 protein, Protein smg-8 homolog, Recombinant Human SMG8 Protein
Supplier:	Absea
Supplier-Nr:	PP-7136-L

Properties

Conjugate:	No
Host:	E.coli
Species reactivity:	human
MW:	19.5 kD
Format:	Lyophilized

Database Information

KEGG ID :	K18734 \| Matching products
UniProt ID :	Q8ND04 \| Matching products
Gene ID :	GeneID 55181 \| Matching products

Handling & Safety

Storage:	-20°C (protect from light & moisture)
Shipping:	+20°C (International: +20°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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