SMG6 (human), recombinant protein

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ABS-PP-6511.20	20 µg	-	-	-	Request delivery time estimate		90.00€
ABS-PP-6511.100	100 µg	-	-	-	Request delivery time estimate		180.00€

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Protein function: Component of the telomerase ribonucleoprotein (RNP) complex that is essential... more

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Product information "SMG6 (human), recombinant protein"

Protein function: Component of the telomerase ribonucleoprotein (RNP) complex that is essential for the replication of chromosome termini (PubMed:19179534). May have a general role in telomere regulation (PubMed:12676087, PubMed:12699629). Promotes in vitro the ability of TERT to elongate telomeres (PubMed:12676087, PubMed:12699629). Overexpression induces telomere uncapping, chromosomal end-to-end fusions (telomeric DNA persists at the fusion points) and did not perturb TRF2 telomeric localization (PubMed:12676087, PubMed:12699629). Binds to the single-stranded 5'-(GTGTGG)(4)GTGT-3' telomeric DNA, but not to a telomerase RNA template component (TER) (PubMed:12676087, PubMed:12699629). [The UniProt Consortium]

Keywords:	Telomerase-binding protein EST1A, Ever shorter telomeres 1A, hEST1A, Nonsense mediated mRNA decay factor SMG6, Smg-6 homolog, hSmg5/7a, Recombinant Human SMG6 Protein
Supplier:	Absea
Supplier-Nr:	PP-6511

Properties

Conjugate:	No
Host:	E.coli
Species reactivity:	human
MW:	17.5 kD
Format:	Solution

Database Information

KEGG ID :	K11124 \| Matching products
UniProt ID :	Q86US8 \| Matching products
Gene ID :	GeneID 23293 \| Matching products

Handling & Safety

Storage:	-20°C (avoid repeat freezing and thawing cycles)
Shipping:	-20°C (International: -20°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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