Siglec-10 hFc Chimera, Avi, Human

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
GSC-Z05818-100	100 µg		-		Request delivery time estimate		524.00€
GSC-Z05818-500	500 µg		-		Request delivery time estimate		1,761.00€

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Siglec-10 is a ligand for CD52, the target of the therapeutic monoclonal antibody Alemtuzumab. It... more

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Product information "Siglec-10 hFc Chimera, Avi, Human"

Siglec-10 is a ligand for CD52, the target of the therapeutic monoclonal antibody Alemtuzumab. It is also reported to bind to Vascular adhesion protein 1 (VAP-1) and to the co-stimulatory molecule CD24 also known as HSA (Heat-stable antigen).Siglecs (sialic acid binding Ig-like lectins) are I-type lectins that belong to the immunoglobulin superfamily. They are characterized by an N-terminal Ig-like V-type domain which mediates sialic acid binding, followed by a varying number of Ig-like C2-type domains. Siglecs 5-11 constitute the CD33/Siglec-3 related group, and are differentially expressed in the hematopoietic system.

Keywords:	SIGLEC10, Siglec-like protein 2, Sialic acid-binding Ig-like lectin 10
Supplier:	GenScript
Supplier-Nr:	Z05818

Properties

Conjugate:	No
Species reactivity:	human
MW:	85.8 kD
Purity:	>95% (Bis-Tris PAGE)

Database Information

KEGG ID :	K06749 \| Matching products
UniProt ID :	Q96LC7 \| Matching products
Gene ID :	GeneID 89790 \| Matching products

Handling & Safety

Storage:	-20°C
Shipping:	+4°C (International: °C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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