SIGIRR (human):Fc (human) (rec.)

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
AG-40A-0093T-C010	10 µg		-		3 - 9 business days*		160.00€
AG-40A-0093T-C050	50 µg		-		3 - 9 business days*		330.00€

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SIGIRR acts as a negative regulator of the Toll-like and IL-1R receptor signaling pathways.... more

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Product information "SIGIRR (human):Fc (human) (rec.)"

SIGIRR acts as a negative regulator of the Toll-like and IL-1R receptor signaling pathways. Attenuates the recruitment of receptor-proximal signaling components to the TLR4 receptor, probably through a TIR-TIR domain interaction with TLR4. Protein function: Acts as a negative regulator of the Toll-like and IL-1R receptor signaling pathways. Attenuates the recruitment of receptor-proximal signaling components to the TLR4 receptor, probably through an TIR-TIR domain interaction with TLR4. Through its extracellular domain interferes with the heterodimerization of Il1R1 and IL1RAP. [The UniProt Consortium]

Keywords:	TIR8, SIGIRR, Toll/interleukin-1 receptor 8, Single Ig IL-1-related receptor, Single Ig IL-1R-related molecule, Single immunoglobulin domain-containing IL1R-related protein
Supplier:	AdipoGen Life Sciences
Supplier-Nr:	AG-40A-0093T

Properties

Application:	Bioassays
Conjugate:	No
Host:	Human cells
Species reactivity:	human
MW:	~50 kD
Purity:	>90%
Format:	Lyophilized

Database Information

KEGG ID :	K05169 \| Matching products
UniProt ID :	Q6IA17 \| Matching products
Gene ID	GeneID 59307 \| Matching products

Handling & Safety

Storage:	-20°C
Shipping:	+4°C (International: +4°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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View product citations for antibody AG-40A-0093T on CiteAb

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