SH3RF2 PrEST Antigen

SH3RF2 PrEST Antigen
Item number Size Datasheet Manual SDS Delivery time Quantity Price
ATA-APrEST87820.100 100 µl - -

7 - 10 business days*

247.00€
 
Protein function: Has E3 ubiquitin-protein ligase activity (PubMed:24130170). Acts as an... more
Product information "SH3RF2 PrEST Antigen"
Protein function: Has E3 ubiquitin-protein ligase activity (PubMed:24130170). Acts as an anti-apoptotic regulator of the JNK pathway by ubiquitinating and promoting the degradation of SH3RF1, a scaffold protein that is required for pro-apoptotic JNK activation (PubMed:22128169). Facilitates TNF-alpha-mediated recruitment of adapter proteins TRADD and RIPK1 to TNFRSF1A and regulates PAK4 protein stability via inhibition of its ubiquitin-mediated proteasomal degradation (PubMed:24130170). Inhibits PPP1CA phosphatase activity (PubMed:19945436, PubMed:19389623). [The UniProt Consortium] Buffer: PBS and 1M Urea, pH 7.4.
Keywords: HEPP1, SH3RF2, RING finger protein 158, POSH-eliminating RING protein, E3 ubiquitin-protein ligase SH3RF2, RING-type E3 ubiquitin transferase SH3RF2, Heart protein phosphatase 1-binding protein
Supplier: Atlas Antibodies
Supplier-Nr: APrEST87820

Properties

Application: Control antigen
Conjugate: No
Host: E.coli
Species reactivity: human

Handling & Safety

Storage: -20°C (avoid repeat freezing and thawing cycles)
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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