SH3RF2 (human), recombinant protein

SH3RF2 (human), recombinant protein
Item number Size Datasheet Manual SDS Delivery time Quantity Price
ABS-PP-3315-L.20 20 µg - - -

10 - 15 business days*

115.00€
ABS-PP-3315-L.100 100 µg - - -

10 - 15 business days*

205.00€
 
Protein function: Has E3 ubiquitin-protein ligase activity (PubMed:24130170). Acts as an... more
Product information "SH3RF2 (human), recombinant protein"
Protein function: Has E3 ubiquitin-protein ligase activity (PubMed:24130170). Acts as an anti-apoptotic regulator of the JNK pathway by ubiquitinating and promoting the degradation of SH3RF1, a scaffold protein that is required for pro-apoptotic JNK activation (PubMed:22128169). Facilitates TNF-alpha-mediated recruitment of adapter proteins TRADD and RIPK1 to TNFRSF1A and regulates PAK4 protein stability via inhibition of its ubiquitin-mediated proteasomal degradation (PubMed:24130170). Inhibits PPP1CA phosphatase activity (PubMed:19945436, PubMed:19389623). [The UniProt Consortium]
Keywords: E3 ubiquitin-protein ligase SH3RF2, Heart protein phosphatase 1-binding protein, HEPP1, POSH-eliminating RING protein, Protein phosphatase 1 regulatory subunit 39, RING finger protein 158, RING-type E3 ubiquitin transferase SH3RF2, SH3 domain-containing R
Supplier: Absea
Supplier-Nr: PP-3315-L

Properties

Conjugate: No
Host: E.coli
Species reactivity: human
MW: 10.5 kD
Format: Lyophilized

Handling & Safety

Storage: -20°C (protect from light & moisture)
Shipping: +20°C (International: +20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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