Semaphorin 4G/SEMA4G Protein(C-6His) (recombinant human)

Protein Construction: Recombinant Human Semaphorin 4G is produced by our Mammalian expression system and the target gene encoding Val18-Leu680 is expressed with a 6His tag at the C-terminus. Sequence: Val18-Leu680. Fusion tag: C-6His Endotoxin: < 1.0 EU per µg as determined by the LAL method. Apparent Molecular Mass: 90-95 kDa. Protein function: Semaphorin-4G is belongs to the semaphorin family, contains 1 Ig-like C2-type domain, 1 PSI domain, 1 Sema domain. Semaphorins are a large family of conserved secreted and membrane associated proteins which possess a semaphorin (Sema) domain and a PSI domain (found in plexins, semaphorins and integrins) in the N-terminal extracellular portion. Based on sequence and structural similarities, semaphorins are put into eight classes: invertebrates contain classes 1 and 2, viruses have class V, and vertebrates contain classes 3-7. Semaphorins serve as axon guidance ligands via multimeric receptor complexes, some (if not all) containing plexin proteins. This gene encodes a class 4 semaphorin. Protein function: Cell surface receptor for PLXNB2. May play a role in axon guidance. [The UniProt Consortium]