SEMA7A, His, Human

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
GSC-Z05803-100	100 µg		-		Request delivery time estimate		457.00€
GSC-Z05803-500	500 µg		-		Request delivery time estimate		1,505.00€

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Semaphorin7A (Sema7A) plays an important role in the immunoregulation of the brain.Sema7A is... more

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Product information "SEMA7A, His, Human"

Semaphorin7A (Sema7A) plays an important role in the immunoregulation of the brain.Sema7A is upregulated in the epileptic brain and plays a potential role in the regulation of seizure activity in PTZ-kindled epileptic rats, which may be related to neuroinflammation. Sema7A promotes the inflammatory cytokines TNF-alpha and IL-6 as well as the growth of mossy fibers through the ERK pathway, suggesting that Sema7A may promote seizures by increasing neuroinflammation and activating pathological neural circuits. Sema7A plays a critical role in epilepsy and could be a potential therapeutic target for this neurological disorder.

Keywords:	SEMA7A, CDw108, Semaphorin-L, Semaphorin-K1, Semaphorin-7A, JMH blood group antigen, John-Milton-Hargen human blood group Ag
Supplier:	GenScript
Supplier-Nr:	Z05803

Properties

Conjugate:	No
Species reactivity:	human
MW:	69.5 kD
Purity:	>95% (Bis-Tris PAGE)

Database Information

KEGG ID :	K06529 \| Matching products
UniProt ID :	O75326 \| Matching products
Gene ID :	GeneID 8482 \| Matching products

Handling & Safety

Storage:	-20°C
Shipping:	+4°C (International: °C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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