SEMA4B Protein, Mouse, Recombinant (His)

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Item number	Size	Datasheet	Manual	SDS	Delivery time	Price
TGM-TMPK-01034-5ug	5 µg	-	-	-	7 - 10 business days*	46.00€
TGM-TMPK-01034-10ug	10 µg	-	-	-	7 - 10 business days*	72.00€
TGM-TMPK-01034-20ug	20 µg	-	-	-	7 - 10 business days*	114.00€
TGM-TMPK-01034-50ug	50 µg	-	-	-	7 - 10 business days*	222.00€
TGM-TMPK-01034-200ug	200 µg	-	-	-	7 - 10 business days*	673.00€

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Description: Semaphorin 4B (SEMA4B) inhibits the invasion of non-small cell lung cancer (NSCLC)... more

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Product information "SEMA4B Protein, Mouse, Recombinant (His)"

Description: Semaphorin 4B (SEMA4B) inhibits the invasion of non-small cell lung cancer (NSCLC) through PI3K-dependent suppression of MMP9 activation. SEMA4B may induce FoxO1 nuclear retention through suppressing PI3K/Akt signaling pathway, which subsequently inhibited cell growth through the direct nuclear target of FoxO1, p21. A role of SEMA4B in suppressing NSCLC growth, besides its role in inhibiting cell metastasis, and highlights SEMA4B as a promising therapeutic target for NSCLC. References: Jian H, et al. SEMA4B inhibits growth of non-small cell lung cancer in vitro and in vivo. Cell Signal. 2015 Jun,27(6):1208-13. doi: 10.1016/j.cellsig.2015.02.027. Epub 2015 Mar 4. PMID: 25746385.

Keywords:	SEMA4B , SemC , Semaphorin-C , MGC131831 , Semaphorin-4B , KIAA1745 , SEMAC
Supplier:	TargetMol
Supplier-Nr:	TMPK-01034

Properties

Conjugate:	No
MW:	75.7 kD

Database Information

KEGG ID :	K06521 \| Matching products
UniProt ID :	Q62179 \| Matching products
Gene ID :	GeneID 20352 \| Matching products

Handling & Safety

Storage:	+4°C
Shipping:	+4°C (International: +4°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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